Name: HGH 40IU x 10 (400IU)
Brand: RetaLABS
SKU: hgh-40iu-x-10-400iu
Price: 750.00 AUD
Availability: InStock
Rating: 4.6 (5 reviews)

Question 1

What is HGH 400IU?

Accepted Answer

A research kit of 10 vials, each 40IU of lyophilised recombinant human growth hormone (somatropin), 400IU total. Somatropin is a 191-amino-acid, ~22 kDa protein supplied for laboratory research use only.

Question 2

What is recombinant HGH used for in research?

Accepted Answer

Research-grade recombinant human growth hormone (somatropin) is applied in studies across the GH and IGF-1 signalling axis. Metabolic research uses it in lipolysis models (GH-stimulated fatty acid mobilisation from adipocytes), protein synthesis assays, and glucose homeostasis studies where GH's interactions with insulin signalling are under investigation. Body composition research examines GH-driven effects on fat distribution, lean mass accretion, and differential adipose tissue dynamics. In endocrinology it functions as a bioactivity reference standard for receptor binding and competitive inhibition assays at GHR and IGFBP targets. Cell culture applications include downstream IGF-1 production by hepatocytes, GH receptor internalisation kinetics, and JAK2/STAT5 pathway studies in somatotropin-responsive cell lines.

Question 3

How is recombinant HGH different from pituitary-derived GH?

Accepted Answer

Recombinant HGH (somatropin) is synthesised via recombinant DNA technology, expressed in E. coli or mammalian systems from a plasmid encoding the 191-amino-acid GH sequence. It is structurally identical to pituitary-derived GH in primary sequence and tertiary four-helix bundle conformation that drives GHR binding. The historical alternative, cadaveric pituitary-derived GH, was discontinued following Creutzfeldt-Jakob disease (CJD) transmission events linked to contaminated preparations. Recombinant production eliminates prion and pathogen contamination risk entirely and delivers highly reproducible batch-to-batch purity confirmed by HPLC. Researchers can rely on the 191-AA recombinant standard for consistent, literature-comparable results across experimental runs.

Question 4

What is the recommended storage for HGH?

Accepted Answer

Lyophilised recombinant HGH (somatropin) requires refrigerated storage at 2–8°C, freezing at −20°C is not appropriate and risks disrupting the protein's four-helix bundle tertiary structure essential for GHR binding activity. Refrigeration at 2–8°C maintains stable native conformation throughout the lyophilised shelf life. Avoid light exposure and temperature excursions in either direction. Once reconstituted with bacteriostatic water, solutions should be kept at 2–8°C and used within 3–4 weeks; do not freeze reconstituted HGH as this promotes irreversible protein aggregation and loss of bioactivity. Prepare reconstituted volumes as needed for each experiment rather than bulk-preparing in advance.

Question 5

How should HGH be reconstituted for research?

Accepted Answer

For research reconstitution, draw the required volume of bacteriostatic water and inject it slowly along the inner wall of the lyophilised vial (directing the stream down the glass and onto the powder rather than jetting it directly at the cake, which can cause localised denaturation. Allow 30–60 seconds of passive dissolution before gently swirling the vial in slow circular motions to complete dissolution. Avoid vigorous shaking) somatropin is a large 191-amino-acid, ~22 kDa protein with high susceptibility to agitation-induced aggregation compared to smaller peptides. The fully dissolved solution should be clear and colourless.

HGH 40IU x 10 (400IU)

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